Abstract
Background:
Stroke is a non-traumatic, focal vascular injury of the nervous system and typically results in permanent damage in the form of cerebral infarction or intracerebral hemorrhage and/ or subarachnoid hemorrhage. This study was aimed to measure the ferritin Level among Sudanese patients with the ischemic stroke.
Material and method:
This was a case control hospital based study conducted at Ribat University Hospital at Khartoum state during the period of December 2022 to April 2023, It included all patients attending Ribat University Hospital and diagnosed with ischemic stroke during the aforementioned period as case group and compared to apparently healthy individuals with no history of thrombi or stroke as control group. Roche kits on the Hitachi 912 clinical analyzer were used for serum ferritin measurement.
Results:
Serum ferritin levels mean in the case group was (232.3± 36.3), in the control group was (114.1±11.7). Comparison between case and control in ferritin levels showed highly significant increase in the case group (p. v= 0.004) .Insignificant differences in ferritin levels between cases and controls in gender, past medical history and risk factors (p. v > 0.05) were shown. A negative correlation of ferritin levels was detected with age (p. v >0.05).
Conclusion: This study demonstrates the significant rise in serum ferritin in ischemic stroke Sudanese patients when compared with control, and the ferritin level had insignificant correlation with gender, age, past medical history and risk factors.
Keywords
- ferritin
- ischemic stroke
- genetic factors
- risk factors Hypertension
- diabetes mellitus