Correlation of Platelet-to-Lymphocyte Ratio (PLR), Neutrophil-to-Lymphocyte Ratio (NLR) to Gleason Score in Prostate Cancer Patients at Haji Adam Malik Medan General Hospital

Robby Anggara; Robby Anggara; Syah Mirsya Warli; Syah Mirsya Warli; Ginanda Putra Siregar; Ginanda Putra Siregar

doi:10.18535/ijmsci/v5i5.14

Abstract

Introduction : PLR and NLR have been shown to be scientifically significant as prognostic factor in patients suffering from Prostate Cancer. In other side, Gleason Score is the main parameter in determining the prognosis of patients with prostate cancer. In this study, we will analyse the correlation of PLR and NLR to Gleason Score in prostate cancer patients.

Method : This study was conducted by using the cross-sectional method at the Department of Urology of H. Adam Malik General Hospital Medan in 2012 until 2017. We analyzed 38 samples that met inclusion and exclusion criterias using spearman correlation test and Kaplan-Meier Curve test for Survival Rate analysis on Statistics SPSS ver 21.

Results : From 38 samples analyzed, we found the relationship between PLR and NLR with Gleason Score (p <0.001, with R 0.675 and 0.607 respectively)

Conclusion : Increased PLR and NLR scores had a significant association with Gleason Score in Prostate Cancer patients